Top Definition
An interjection expressing extreme indifference to or disdain of another person's ideas or presence. Also can be used to express displeasure about a situation. (Note: the T and S must both be clearly pronounced.)
Creepy guy: Hey girl you got pretty eyes, can I get your number?
Christine: Tsuh.

Steve: Dude check out my star wars toy collection!
Ted: Tsuh.

Jenny: WTF, this bar is out of Stoli Orange?!?
Mandy: TSUH!
by salademanders November 21, 2010

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