Top Definition
Usually occurs when one of your friends on MySpace constantly changes your position in their topfriends, and you get pissed off. Symptoms include leaving hateful comments and/or messages on their page, moving them around in your top friends, or completely taking them off of your top friends list.
Kyle saw that he was moved to last place on Nikki's top friends list and instantly developed Top Friends Syndrome (TFS). He in turn moved her to last place on her list after bitching about it to everyone he knows.
by kupcayq August 07, 2007

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