a mixture of blood, sweat, spit, and semen. usually added to one's drink as a cruel joke
Ron: Hmm, this drink tastes a little weird and its sticking to the roof of my mouth. whats in it?

Dale: thats cause its a Tijuana Cocktail!

Ron: Motherfucker!
by Lightnin' J October 20, 2007
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a mixture of spit, sweat, and semen. usually given to or added to one's drink as a cruel joke
Jack: Ugh, this drink tastes like shit! What is it?

Bob: Its a Tijuana Cocktail Bitch!
by Lightnin' J November 7, 2007
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