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1.
Getting a 24 pack of Dr. Thunder from walmart, then shaking the cans and throwing them out the window of a speeding car. Usually mailboxes and signs are the targets, but Dr. Thunders can also be thrown at cars and pedestrians.
1: Hey, wanna go for a thunder run?

2: Yea, let me go to walmart and get some more people

1: but my car cannot fit 4 people.

2: who cares, the more the merrier on a Thunder Run.
by paco789456 June 29, 2010
 
2.
A high speed military convoy utilising heavy weapons, armoured vehicles and offensive tactics to reach a destination, most likely along a route of extreme danger. The strength, speed and intensity of the attack, coupled with the use of formidable weapons and equipment quickly overruns the surprised defending force.
The 3rd United States Infantry Division made use of the Thunder Run tactic to seize Baghdad from Iraqi forces, on the 5th of April 2003
by chargrilledawesome April 14, 2013
 
3.
Diarrhea acompanied by: Loud, Hard Farts, whose volume is intensified by the toilet bowl.
Jesus Christ!
What?
Did you hear Little Timmy in the Bathroom? It sounded like he had the Thunder Runs...
by Marsexxxy23 March 12, 2010
 
4.
Having sexual intercourse twice with the same person in a short period of time.
"Last night, Leah and I went for a Thunder Run"
by IanR December 01, 2006