The act of going the bathroom, specifically for a shit. Comes from LeBron James using this phrase to take a massive shit on a huge number of people: fans, teammates, and the entire NBA.
Bro #1: It's time for that bitchin' party!

Bro #2: Yeah! One sec though, I'm taking my talents to South Beach first!
by Disappointed Ohioan October 27, 2010
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THE OFFICIAL CLEVELAND DEFINITON - Taking a shit.
(Also referred to as "Making LeBron a Free Agent)
Damn, that Chinese food is upsetting my stomach. I'm taking my talents to South Beach. Now, where's the nearest toilet?
by The Encyclopedia Cuyahoga August 19, 2010
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to betray, to defect
Hey bob, do you want to play for our team? We don't have any good players.

<joins opposing team> Sorry, I'll be taking my talents to south beach.
by piximon July 9, 2010
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The infamous words uttered by LeBron James as he broke the hearts of every person in the Cleveland area, that shall henceforth be a euphemism for Masturbation.
Mike has been in a long drought and ended up striking out last night too. So he went home, put on some porn, and said to himself, "I'm going to take my talents to South Beach"
by blaze1984 July 11, 2010
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