Top Definition
Noun. Also TWoPer. A fan who takes part in the "Television Without Pity" forum.
I hate Saleisha's simpering, cutesy brand of arrogance as much as the next TwOPper, but that makeover was cruel.
by SharleneSanFrancisco October 16, 2007
A large vagina.
That guy's got a whopper, but that lady has a twopper.
by Treps84 January 27, 2015
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