Top Definition
Acronym for "testicle, left, suck it." Both the acronym and the statement itself should be used as a response similar to "suck my dick." If the full statement is used, it must be said slowly and with distinct pauses between each comma.
Nate: Yo, Jamal! You see all dem bitches I was wit last night?
Jamal: TLSI, Nate. TLSI.
by WilliamForrester August 25, 2011
9 Words related to TLSI
Too late seen it. often used online when someone links you to an image what you've already seen.
Guy1 "Hey dude check out this cool image"
guy2 "TLSI"
by Jezaroo_666 January 20, 2008

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