Top Definition
When texting or messaging a friend who doesn't respond for a period of time because of taking a lot of drugs, stand for Too High To Reply.
Nick: I couldn't get a hold of Matt.
Josh: Is he THTR?
Josh: Is he THTR?
by nmjohn
April 20, 2008
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2
Too high to respond
Hey Kristen! How did it go? And what did she say?
T.H.T.R
T.H.T.R
by TheStoner3
October 13, 2011
