A shortened / abbreviated 2 syllable version of the standard 'WTF' which is composed of 3 syllables. Most known for its use by Eric Cartman, a fictional character of a boy from the animated cartoon series South Park.
TFQ differs from WTF in such a way that TFQ is often used for repeated situations of amazement or disappointment, whereas WTF is most commonly used as the first way of expressing ones level of amazement (or disappointment).
"so she sat down and started to piss, and the bastard drunk it all!"
"yeah, and then she took a shit in his mouth"
- "dude...TFQ... that just ain't cool... she didn't even properly introduce herself.."
Me: Beer tastes like piss and crackers but I drink it anyways.
Eric: "Beer tastes like piss and crackers but I drink it anyways." QFT