1.To be strongly intoxicated. Most commonly refers to being inebriated from alcohol but can be used to refer to other drug intoxication.
2. To be highly confused or confounded.
Refers to the word "swerve".
1. Wow, Fred just drank a 5th of cheap whisky and is now trying to take bong rips. His ass is swizzerved.
2. Man... this quantum physics test has got me swizzerved.