Top Definition
No one truly know what the word "Spwee" means, it's sometimes referred as an acronym for Safety Procedures for Working on Electrical Equipment.

The true meaning of the word Spwee is the username that a gamer made up when the first xbox came out.

It is also sometimes used by facebook/furfags girls that use it to make known how random they are.
I just love Invader Zim ~SPWEE =O
by Spwee1494 April 05, 2010

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