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1.
Very similar to Bad Ass Mother Fucker only instead of being a Bad Ass your a Smart Ass (and not a bad kind of smart ass).
guy 1 "John can do particle nuclear physics in his head while high!"

guy 2 " Yeah John is one Smart Ass Mother Fucker"
by Jesus37295 December 31, 2009

Words related to Smart Ass Mother Fucker

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2.
Someone who is acting like a gay smartass.
Joe: It looks like he is saying kiss me kiss me.

Chris: Smart Ass mother fucker.
by the cool Ratman April 03, 2007