Top Definition
A girl who has both A high number of sexual partners and a higher IQ to match. She likes sex, but she can also ace that Calculus test next week.
Chris: Dude! Sam is so Slutty-Smart!

Adam: How?

Chris: She has been with like 6 guys all through high school and she has a 4.0 GPA!

Adam: DAMN!!!
by Silver Chram April 09, 2010

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