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1.
Scum of the earth, worse than a cunt or whore, genderless, self-serving individual who is incapable of compassion, empathy and any natural human logic or emotion.
I am disgusted by you, no rather you are a complete slizzo, fuck off and die!
by Eves1desire October 11, 2005
 
2.
slut, whore, skank, all around nasty woman
the slizzo gave me head last night.
by Anonymous March 11, 2003
 
3.
penetrating a man's asshole while he sucks his own dick.
after many months of training, the yoga teacher slipped stephen the slizzo.
by dr.clacksnack September 26, 2013