the act of creaming the thick layers of the cuntasoris
Joe: "I sistine chapeled that Huck girl last night."
Cody: "REALLY? how was she?!?"
Joe: "Just alright"
by The Pussy Monster meOWW January 2, 2011
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When a man takes such a massive shit that he must flush the toilet half way through and then continue shitting because he's afraid that the turds will pile up so high in the bowl that they may make contact with his junk as it hangs down into the toilet. Much like the fingers of Adam and God on the ceiling of the Sistine Chapel.
Guy1: dude why'd you flush twice did it really smell that bad?

Guy2: nah man it was a Sistine Chapel Shit.

Guy1: ahh!!! I See.
by Yahbo October 29, 2010
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The act of double finger blasting a girl with your close friend. His finger is in her buttand yours is in the vagina and you can feel the tips of your fingers touching through her
Coleman and I are about to Sistine Chapel this girl.
by BroncoBilly November 11, 2017
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When you’re having sex with a pregnant woman and have your hands on her body and the baby reaches out to touch your hand.
“Dude me and my wife had sex for the first time since she got pregnant but my son sistine chapeled me and totally ruined it.
by Theycallmesmexy November 10, 2021
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The moment a baby touches your hand from inside the womb while having sex’s.

(In reference to the art piece by Michelangelo, The Creation of Adam found in the Sistine Chapel.)
As stated by Mike Cannon during a comedy skit on TikTok.

“I don’t know about you guys, but my optimal way to orgasm is not while I’m Sistine Chapelling with my unborn kid”
by Mow Mow is stressed out November 13, 2021
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the act of smearing or throwing feces onto or at the ceiling of a public bathroom. if done to a business you must call them and let them know they have been "Sistine Chapled" !!!
i could smell it ...then looking up i saw the splattered turd ...then i knew the McDonalds had been Sistine Chapled !!!
by jaysin shuttlecock March 26, 2014
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