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12.
1. a female sibling

2. a female friend that acts like, loves you like, and treats you like a sibling.
I don't have any sisters.

My best friend is like a sister to me.
by King's Daughter June 20, 2005
415 416
 
1.
A person created by your parents for the sole purpose of giving you a convienient girlfriend.
Boy: Let's have sex!
Sister: Ok...but that's the twelfth time today, not counting the anal!
by Pansy and Proud March 31, 2006
1235 995
 
2.
creations of satin designed to search and destroy the older sibling
my sister is eating my arm
by neiketto23 March 13, 2009
580 439
 
3.
How Allie and Erika describe their secret lesbian relationship.
Allie: Oh, oneesan! Feel me up! All the cute green eyed boys are so fickle or homosexual! We're sisters!

Erika: Oh my imouto, I am simply not in the mood! I need to watch more anime sex scenes with my grunting father! He lives for nothing but the climax!
by Allie Caulfield February 09, 2008
326 220
 
4.
a strange alien species which is out to wreck male human life.
my sister is an alien out to ruin my life.
by Orangutan February 17, 2006
570 508
 
5.
your sister is the girl that will always be there for you and may save you one day, wether you know it or not. your sister may or may not be related to you and could just be an amazing friend, but either way your sister is always slow to judge and quick to forgive. she will always love you, she might just hide it from you.
stevi is like my big sister, i love her and always will.
by jennifurrrr December 23, 2006
835 801
 
6.
A female with whom you share parents. Depending on the birth order she can be 1. your friend or 2. the BIGGEST BITCH EVER.
1. My sister is going to take me to see Iron Man 2.
2. My fucking sister just stole my wallet.
by 2buckchuck July 29, 2010
212 184
 
7.
Some girl who thinks that just because she's related to you, can just waltz into your house and eat all the strawberry flavored yougurts when she knows that thoes ones are your favorites!
You know your sister has broken into your house when

A. You turn on the TV and it's set to the Style Network.
B. There's tire tracks on your lawn.

C. Your cat's liter box has a human poo in it.
D. All the strawberry yogurts are gone.
by Woodrow Thrillson June 26, 2010
163 151