Top Definition
An ugly sister, whether it be your own sister or the sister of a friend.

A sisquatch often displays manly physical features, such as a pronounced jawline, broad shoulders, or large muscle mass throughout the body.
"Hey, I just found out that Tony has an older sister!"

"Well, is she hot?"

"Nah, she's a total sisquatch. You're gonna want to stay away from this one."
by N2MT December 11, 2011

Free Daily Email

Type your email address below to get our free Urban Word of the Day every morning!

Emails are sent from We'll never spam you.