Top definition
Sethko is the combination of Seth and Nieko. Seth is the story character from the Twilight series Eclipse, and Nieko (Nieko Hayer) is the aspiring actor who many fans demand get the acting part of Seth Clearwater.
Chatroom:

BlueSphere: Hi There.

Muffic_Sethko: Yo.

RMS_Sethko: Hey!.

Twi05TeamSethko: WAZUP

BlueSphere: What the hell is with your user names?

RMS_Sethko: What's up with YOUR user name.

Twi05TeamSethko: Seriously, noob!

Muffic_Sethko: Only fags don't know what Sethko is.
by BananaNutMuffic July 16, 2009
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