Serenity is based about 500 years in the future, where the government totally takes over human kind and where the human kind exists in multiple solar systems. It focuses in on Serenity, a spaceship where Mal, Inara, Wash, Zoe, Kaylee, Jayne, and Book live as they try to avoid the Alliance. They pick up two people: River, who was experimented on and tortured into insanity by the Alliance, and Simon, her brother who rescued her. They are both wanted fugitives and must avoid the Alliance at all costs, even if that puts Serenity's crew in danger.
Wash: This landing is going to get very, very interesting.
Mal: Define interesting.
Wash: Oh God, oh God we're all gonna to die?
Mal: How about you, darling, ready to go?
River: There's no pattern to the pebbles here… It's all completely random. I tried to count them but you drove too fast. Hummingbird.
Mal: Right, let's go.
(While being attacked)
Simon: My one regret in all of this is never being with you.
Kaylee: With me? You mean to say, as in... sex?
Simon: I mean to say—
(Kaylee cocks her gun.)
Kaylee: Hell with this. I'm gonna live!
Mal: Do you want to be in charge of this ship?!
Mal: Well... you can't...
"I can get you some reallly dank shit but not any of that fake stuff."
(the wanna be stoner sits quietly, confused because he/she is a dumbass)
(2) In Yu-Gi-Oh!, Joey's (Jounouchi) blind sister who is born with an eye defect and that is recified by an expensive operation paided for by his brother. Tristan (Honda) and Duke Devlin (Otagi) wants to date or lay her.
(2) Serenity is born with a genetic or congenital defect.