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1. Sepo
American. (Australian cockney rhyming slang.) From: Yank --> Tank --> Septic Tank.
Is he a Candian? No, he's a Sepo.
by The Linguist Aug 16, 2003 add a video
2. Sepo
American's
fucking sepos
by donny bonny May 25, 2003 add a video
3. sepo
1. a name given to Americans that talk alot of shit, have monstrous horse teeth and complain about everything.

2. a term often used when talking to or about Jake Bryant
dont tell that sepo Jake that where going to the party
by darren Jun 27, 2004 add a video
4. Sepo
an adverb. stupid irrational, crazy, irrating confronting, person
that was one sepo muthafucka
did you see that cunt go all sepo on his ass
by dave Dec 22, 2002 add a video
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