When you either start or hear someone start a sentence with this you know that you/they have had enough and everyone else should shut up or preferably get out of the area
Usually souted at the highest possible level "Oh for fuck's sake how many motherfucking son of a bitch twatting cunting shit licking times do i have to tell you ... shut up"
by Jason Hackett November 1, 2007
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Used as a general term of exclamation or surprise similar to oh my lord, or oh my goodness, or oh shit. Mostly used by people in the 1930's, 1940's, and 1950's. Possibly a minced oath (softened form of swearing) substitute for "For the Lord's sake."

See also land sake.
Land sakes alive, my grandmother said. That sure was a swell sunset.
by Bret_in_Mesa January 3, 2008
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Another saying when a situation captures you by suprise in such a way you have to say these words instead of another gruesome cuss words.
by Noah77 November 18, 2013
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Someone who has no fucking purpose. Derived off of sake which usually means way of living or purpose.
“Fuck you Michelle, you fuck sake.”
by xXdontfuckwithmecuntXx December 30, 2017
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Doing something for the purpose of being ironic.
- "Hey man it's Terry Fox Memorial Day!"
- "Yeah, I'm going to light up a cigarette on the run for the sake of irony. Then I'd really be running for cancer."

- "Hey man, wanna join me in enjoying some Rum and Codeine?"
- "A codeine party? Well, I just came back from my school's drug presentation and a big portion of it was on opiates and Codeine, but for the Sake of Irony I will oblige!"
by Ironic Anonymous October 13, 2009
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This is what you say when you pissed of at some dumb fuck

Like the dumb fuck that says the expression is for fuck's sake's. Nooo
Its for fuck sake!!
Ahh for fuck sake mate , are you stupid
by Ilovebec June 16, 2017
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A term used in a time of despair, anger or frustration. often associated with annoying twats.
I forgot my stuff for today, For Fuck Sake Linda!
by tablecatman February 28, 2017
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