Prounouced buth-ole, he is the patron saint of defecation. In times of constipation, one prays to him and consumes offerings of coffee and/or lubes up one's anus with vaseline as a sacrament to him. When defecation occurs, this is called 'a visit from Saint Butthole'. His imminent arrival is often signaled by pungent flatulation.
"Sorry about the mess, dude. I hadn't shit in three days, but when i did Saint Butthole visited me with a vengeance!"

"Saint Butthole, I apply this vaseline to my anus in the hope that you will send me a glorious poo that will be smoothly and cleanly delivered from my butt..."
by Professor Poo January 03, 2008

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