Top Definition
Medical slang for "Sorry Motherfucker, You're On You're Own". Used when someone has been injured so horribly, there is nothing a doctor can do.
The man was hit by a train, then flung onto the interstate, where he was hit by 6 semi trucks before rolling off the bridge into the river below, being bitten by a water snake, and getting creamed by a speed boat. After he was brought to the hospital, he was diagnosed with SMYOYO syndrome.
by NINJA_CARROT August 09, 2009
6 Words related to SMYOYO syndrome

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