Top Definition
The females around the Dade City area that feel as though they run the streets. Often times a young Italian male will be minding his own business and then out of no where... BOOM! The young handsome Italian male has just been shouldered to the ground by a burly female who runs the street. The young Italian male gets up and then causes a scene by vowing to beat the shit out of the next bitch that thinks she runs the street.
Sid: What the fuck!! Did you guys just see that??

Group: No, what happend?

Sid: I just got shoulder by one of these SLU bitches doing the SLU Street Running!! I swear, it seems like the SLU bitches just own the street sometimes!!!

Group: What the fuck!?
by Grinnell April 15, 2008
5 Words related to SLU Street Running

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