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Severe hardening of inner toe. this is a condition affecting people who have unusually large callusses on their big toe, usually on the inside edge. S.H.I.T. sydrome is characterised by extremely hard skin which is usually impervious to the normally painful effects of peircing via stray staples or pins. Squash and tennis players are most commonly affected by shit syndrome.
'Whoa man, I just stood on a fishhook and hardly felt a thing!' 'You must have S.H.I.T. syndrome man.'
by Sean, Jye October 19, 2006
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