Top Definition
A mens group consisting of more than 2, but less than 4. All of which utilize a prescribed instrument in such a manner to emphasize the better things in life. Such as "Admiral Nelson", or an awesome "Club Sugarland".

Running the Gambit is about as awesome as mediocrity can offer, or afford.
"These guys sound like they're Running the Gambit"
"That's because you're high"
by One of the three. In a bar March 10, 2010
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