To rob someone.

Also a dope hip-hop group.
"Yo dawg, I'm about to run the jewels on this broad walking by"
"Nah son, you don't want to do that, you'll get locked up for years"

"The new album by Run the Jewels is amazing. Killer Mike and El-P at it again."
by lastblockbuster November 2, 2014
Get the run the jewels mug.
An expression used when robbing someone to denote the desire that he or she relinquish the jewelry that he or she posses.
Run them jewels nigga! Give me them watches, them rings, and bitch...Give me that motherfuckin' necklace!
by brian fury May 19, 2005
Get the run them jewels mug.