Top Definition
When you laugh at peoples misfortunes. An example would be laughing at people that has a problem with Murphy's Law. It is not funny to the person with the Murphy Law but it is funny to the person with the Reina Syndrome and are usually un-aware of having the Syndrome
"Ouch, I just banged my toe and hit my head." - Guy 1
"BAHAHAHAHAHAHAHA!!" - Reina
"Does she have Reina Syndrome?" - Guy 3
"I think so." - Guy 1
"No I don't." - Reina
"Yes you do." - Guy 1 and Guy 3
by Stunerequant June 19, 2011

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