Top Definition
An acronym for "Rolls in Space Laughing," this addresses the lack of planar surfaces in space which can be co-opted as an absolute point of reference when attempting to ROFL in zero G.
Neil Armstrong had to RISL as he was selected to be the first man to step foot on the moon in the Apollo 11 mission.
by Thracks August 23, 2007
1 more definition
7 Words related to RISL
Acronym for "Rolling in Shit Laughing"
Need you ask more?
lol.

ROFL.

RISL!
by no.mop February 01, 2008

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