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The area / neighborhood of Manhattan, New York bordered by the Queensborough Bridge to the south, Central Park to the west, the East River to the east and E 72nd St to the north. It is a section of what is generally considered the Upper East Side. QuoBoNo is derived from the "QU" and "BO" in QUeensBorough Bridge, the major feature of the area. The "NO" indicates that the area is north of the Bridge.
"Hey, is that party tonight in TriBeCa?"
"No, its in QuoBoNo"

"I heard Dan just moved into the city."
"Yeah, he found a great deal in QuoBoNo"
by GetFritzy August 05, 2009