Top Definition
A take off on Jennifer Lopez's "J-Lo". Prez-BO is the hip "street" name given to President Barrack Obama by conservatives.
Guy #1: "Did you hear about that crazy shit Obama is trying to pull with the cap and trade thing?"

Guy #2: "Geez, I guess that's Prez-BO's idea of change you can believe in."

Guy #3: "No shit, change is all I got left in my pocket."
by The Original Big Daddy G July 10, 2009
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