Top definition
Running to the bathroom for a quick snort of cocaine.
Mary: "Jen, I'm going to go powder my nose. Wanna come with'?
Jennifer: "Why do you have a straw for?"
Mary: To snort some of this awesome blow I just scored."
by K4t333 January 24, 2011
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2
Go to bathroom and snort drugs
Am going to go to the bathroom and powder my nose - Mia Wallace, Pulp Fiction
by V Chen November 23, 2016
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3
A sarcastic euphemism for going to drop a deuce, have a private conversation, or simply jet from a situation (typically a table).
(At a restaurant)
Man on date: The dividends on my Facebook stock payed my dues for the swingers club this year.
Woman on date: Excuse me, I'm going to go powder my nose.
by RobDestiny April 10, 2017
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