The anal administration of any drug. Most commonly done with MDMA, DMT, or 2cb
Plugging DMT is an effective way to skirt using an MAOI to achieve an ayahuasca like high which is less intense but much longer lived than vaporizing it.
by Rimjob Jesus February 4, 2010
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a monogamous couple. where the man is the plug and the woman is the plug in. there genitalia is pluged into each other and no one else's. Derogatory.
larry and betty are plug and plug-in.
by Deep Blue 2012 July 13, 2009
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The phrase "plug it" refers to when one chooses to start rolling (consume ecstasy) by putting the pill (also known as a "bean") into the anal cavity to "roll harder". Contrary to belief, this method actually helps one roll harder and longer.
"Alright man, I scored four beans. What are you going to do with your two?"
"Dude, don't laugh but I'm totally gonna plug it."
"Oh man, bro. Have fun and wash your hands when you get back, okay?"
by Gabriel R. September 20, 2008
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The insertion or other voluntary introduction of foreign matter into the anus or vaginal cavity for the sole purpose of recreational misuse(or use) of said item/substance. Similar to butt chugging, with the exception of using non-liquidous matter instead of alcoholic beverages.
Chad took a dump so he could start plugging a few hits of MDMA before he went to the rave.

My girlfriend read online that she would get better results from her pre-workout powder by plugging it instead of drinking it.

Last time I went to a party in college, I had a girl plug cocaine before we had sex and she got super high and my dick went numb.
by DanMarinoJr December 13, 2017
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To take amphetamines
Wanna plug in and watch The Sopranos from start to finish?
by Queen Buttrix January 18, 2021
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-When someone hooks it up with something you need, or does a really nice favor.

-When the weed dealer puts in more weed in your sack, its called a "plug".
You gave me 10 bucks?? PLUG!
by nastynate011 January 1, 2011
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A girl that likes to take CUBED times said amount of butt plugs that are already in use.
Boyfriend: Oh baby, Jenny; lets Plug³ this sweet teen asshole of yours.
Girlfriend: Sure, babe *moans loudly*
by LightBeUponYouAndYou February 27, 2017
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