Fast food items found on the floor of your car that look exactly the same as they did a year ago when they fell out of the bag
by Fry_cook January 13, 2014
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Someone who has done so much acid, even when not tripping, they think differently and the effects of acid still seem in effect.
jimi Hendrix has done so much acid! He's definitely a permafry.
by Mashiss March 25, 2015
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A person who has taken and abused drugs for so long that they achieve a permanent state of "highness" whether they are on drugs or not. They are literally a little bit "munted" forever...
by TinkaBell January 9, 2017
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Permanently-Fried. When you do so much acid you never come down completely and are never the same. Does NOT mean flash-backs, that's different.
He did way too much acid a few years ago and he's been permafried ever since.
by rubicante June 14, 2003
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Being stoned so often that your mental state is permanently altered.
The Red Hot Chili Peppers are probably permafried by now.
by Salieri_82 May 27, 2006
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When you smoke so much weed that you permanently seem high when sober, permanent stoner eyes (closed ish eyes) and permanent stoned behaviour, people may ask you if you're stoned when you're sober if you're permafried
Charles: whats up with Greg's eyes?
Neil: oh he's permafried thats why, hes actually sober rn
by Glitxh February 10, 2023
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To have taken so many drugs your brain is irreversably fried
John Saunders went way too hard for way too long but hasnt touched drugs in 10 years. Even after such a long period of sobriety he shows signs of serious brain damage and as such is permafried
by rocketdogz September 21, 2010
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