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A common expression among the g's, it means im going to insert my penis into your cranium in a rather forceful manner.
I have a headache after you penis'd me in the head!
by little_chris October 20, 2004
if you tell some one "penis you in the head" you are telling him to go screw himself.
john: can i sleep at your house tonight?

bob: no! now penis you in the head!
by medalist October 19, 2004