An enema performed in a sexual way by pissing in an asshole.
Dude look at her! I would totally pee in her butt. I just drank a 2 liter of diet coke, and I am ready to fuckin explode and give her a penema.
by rogerthewhale November 25, 2013
When a male administers an enema on another male or female by inserting his penis into their anus and urinating.
They ran out of fleet at the porn shoot today so I had to penema the broad before the anal scene.
by DeePFRieD November 07, 2007