Top Definition
The inflammation of panzy-ness in a person.
This leads to one becoming weak, fat, lazy and gaining higher estrogen levels.

The inability to man the hell up and do what you gotta do.
Danny has a massive case of panzitis and won't come out with us for a run.

A: Is Ben still injured? I thought he just bruised his toenail...

B: Yeah he's come down with a bad case of panzitis.
by jcho85 June 30, 2009
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