Top Definition
When a person is annoying me specifically
He keeps interrupting me when I am busy, so he is a pain in my ass.
#pain in the ass #annoying #pain in the butt #ball buster #nuisance
by Jess Z October 22, 2008
a real pain after a person experienced anal intercourse
Ouch, I need to go to the doctor because I have pain in my ass.
#pain in the ass #analism #hemmorhoid #anal #jackass
by Andav October 22, 2008
Someone whose sole existence is to piss you off and bother you.
John, you are being a really big pain in my ass today.
#husband #youve got a small dick #annoying #go away #irritating #squash you like a bug #ball slap
by Happy wife happy life July 14, 2015
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