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1.
PNE
Small Male Sex Organ,

people who are referred to as pne, are usually people with penises so small they are almost vaginas
Example

doctor: I need to check for testicular cancer.
person: unlikely i'm PNE
by TWTubs February 17, 2010
 
2.
PNE
Positive Negro Experience - This occurs when an African-American, usually in customer service, is very respectful and helpful to a stranger. This experience applies when directed to white people, whereas the same behavior attributed to a fellow African-American can be commonplace.
"I was in Burger King today and I was actually impressed by the politeness and respect that the cashier gave me. This was definitely my PNE for the day."
by Chad778 August 18, 2009
 
3.
1) PNES. pronounced "penis" Term used to start a funny joke about Nintendo's old NES system.
2) Known as a Portable Nintendo Entertainment System
3) Penis.
dude: Wish they would make a portable nintendo...
Anon: They have. It's called a PNES.
dude: O_o
Anon: yes, i said penis.
by We are ALL anonymous December 21, 2008