Top Definition
P.E.N.I.S. - Post Ejaculatory Non-Interest Syndrome.

The post-coital complete lack of interest in the female companion that engulfs the majority of males as soon as their female conquest has brought them to climax
Girl: That was amazing, I love you so much.

(Silence)

Girl: Have you fallen asleep already?

Boy: Nope, just got a bit of P.E.N.I.S. Don't worry about it.
by dangerrouse August 01, 2010
9 Words related to P.E.N.I.S.
Personality, Energy, Neaty, Intelligent, Style
I showed that girl my P.E.N.I.S. and now since we're close, I showed her my penis.
by ithinkyoudiedman July 19, 2008

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