Top Definition
An acronym used instead of tests/quizzes. It originated in a chemistry class, where test/quizzes were never spoken of and OTDYU was the new hot thing. OTDYU stands for "Opportunity to Demonstrate Your Understanding"
Person 1 : Hey do we have an OTDYU tomorrow?
Person 2 : No it's on Thursday. It's worth 80 points, so you better study!
Person 1 : Oh, thanks!
by #Swahh September 11, 2011

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