look up any word, like sex:
 
1.
Oh, but for fuck's sake!
OBFFS! That was totally uncalled for!
OBFFS, just open the goddamn door before trying to enter!
by BobKnudor June 26, 2010
 
2.
Online Best Friend(s) Forever
Losing touch after college, Erin and Trevor reconnected several years later on Facebook and now, communicating strictly via computer, are OBFF.
by Erin and Trevor May 13, 2007
 
3.
Original Best Friends Forever
She was my OBFF before Jennifer was my BFF.
by tweesha March 04, 2010