Drink 10floz(1 bottle) of Vicks NyQuil or 2 bottles for nightmare difficulty, and then quickly try to masterbate before you fall asleep. If you succeed you win!
I got about 20seconds into the NyQuil challenge on nightmare mode before losing, but I was already tired when I started.
by startrestart March 6, 2010
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When you try to do self-checkout, but then they say this item "needs assistance" and they come over and check your i.d. and you're just thinking "Are you kidding me? I just have a fucking cold/flu!"
In order to obtain the Nyquil to treat my flu symptoms, I had to go through the public humiliation of being Nyquil carded, which held up the line and made me feel like an idiot.
by rp1149a February 9, 2012
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Sickness can strike at any moment, in this modern world of fast-paced lifestyles and high-calorie Toasty Quizno's Torpedos.

The only way to ensure a quick rebound from ANY illness that trashes your system is to spring a comprehensive three-day Nyquil Implementation-Protection Situation, or NiPS

Following a stringent daily/Nightly intake of Water, Nyquil, High-Pulp Orange Juice, and Safeway's Signature Spicy Basil Tomato Bisque; mixed with an unwaivering solid social-barrier of X-files and endless hours of unintelligible kaleidoscopic footage of 'Jazz - A Film by Ken Burn'

By the 3rd day of infection one can be assured that a king-hell move of good-health shall force the cause and source of the problem inadvertently deep into a stomach, liberally coated with Nyquil's best and brightest.

The ensuing movement will bring upon a most glorious shit. The Nyquil log, depending on the flavor of your choice, will be green and blue of the deepest pastels. The texture soft, like a fine woven-basket. Rest assured, the evils of the common flu or even tuberculosis will be cured locked away within this hefty guardian-angel of a shitball.

(Also see. Robotripping)
Hey Man, didn't you just get diagnosed with Avian influenza

That was three days ago, by quickly springing NiPS into action I was able to recover, and snapped a pic of my 4.2 lbs "Nyquil Log"

Damn Son... that's a blue shit!
by Jawagas January 25, 2011
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when you take nyquil and don't get enough sleep. the result: nyquil hangover.

results are a feeling of sleepiness/grogginess. persons are usually able to overcome such a feeling by midday. as for the former part of the day, you might as well be living as a zombie.

nyquil hangovers usually fuck you over when you're too anxious for a 7am midterm and you take nyquil around 8pm the previous night but don't fall asleep until 2am. when you wake up, voila, a splendid nyquil hangover.

you feel like shit, so you drink coffee. the coffee does absolutely nothing. so you drink a rebull, the redbull does absolutely nothing. soon you can feel your heart racing from all the caffeine and b12, but you still want to sleep. these are the true side effects of a nyquil hangover
Jenny: Becky what the hell am i experiencing right now?? i feel like shit!

Becky: nigga, you popped too much nyquil, now you got dat nyquil hangover
by Redzone1 June 9, 2009
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A social gathering of usually two or three people where the participants drink more than the recommended amount of Nyquil and fall asleep.
"You're just jealous that you can't sleep with us in here and have a Nyquil party!"
by NoTongue March 1, 2010
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A NyQuil induced state of drowsiness.
That guy was so NyQuil hammered, he fell out his 2nd story window.
by meow!456 October 4, 2011
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The alcohol you use to drink yourself to sleep
"Carson you smell like a bar"
"Yeah I had a bit of a rough night"
"Dude, no alcoholic NyQuil, that stuff will kill your liver"
by Lil Xan's Future Wife July 9, 2017
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