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1.
A term used to decribe the potency of a poisonous substance.

A term used to describe excitement or enjoyment referring to, or of, an event or situation.
The drink was quite noxious and he couldn't have survived.

Damn, yo! That was some wicked noxious shit! Daaammmn!
by Gman October 11, 2004
 
2.
exactly the same thing as obnoxious...
You noxious!
I ain't noxious!
by x39 March 05, 2003