Top definition
(nope-uh-MEEN) The chemical in the brain causing a severe feeling of nope. Levels generally spiked when an individual is exposed to a stimulant, such as a large snake.
Dude, that spider was huge! I just felt my nopamine levels rise.
by RevBran May 27, 2014
Mug icon

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

Buy the mug