Top Definition
(nope-uh-MEEN) The chemical in the brain causing a severe feeling of nope. Levels generally spiked when an individual is exposed to a stimulant, such as a large snake.
Dude, that spider was huge! I just felt my nopamine levels rise.
by RevBran May 27, 2014

Free Daily Email

Type your email address below to get our free Urban Word of the Day every morning!

Emails are sent from We'll never spam you.