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2.
Nippleton is an all-female institute of higher education that bends over backwards to please its students and prepare nubile young ladies for the future.
Nippleton State University
by Mona Licker August 09, 2006
 
1.
A word commonly used to express frustration or irritation towards a friend. Usually used in a joking manner and is not intended to be taken seriously. Can also be used in a friendly way to show compassion towards another person.
1. Dude, stop being such a Nippleton.

2. Come on Nippleton, just come with me.
by Danny Donezo February 10, 2010