Top Definition
When you start a new job at a restaurant as a hostess and within a week you have already slept with at least one of the people that work there.
I just got hired as a hostess at a restaurant on monday and on friday night I slept with the douchiest waiter that works there...yup definitely got a case of New Hoe-stess Syndrome.
by jstringy May 28, 2011
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