Naw Shuff Share definition Flag Anagram. Generally the opposite meaning of the phrase "Sho Nuff". A sad expression used upon the realization of unfortunate circumstances. Doctor: "Sir. Your hamster has tested positive for HIV." Hamster Man: "Naw Shuff... :(" Naw Shuff by Dethday June 12, 2013 0 0 Get merch Get the Naw Shuff mug. Buy Now — $32.95 See more merch