N64itis Share definition Flag (Noun) The pain you get in your thumb after using the analog stick on the N64 controller for too long. I played Ocarina of Time for five hours straight and now I have a bad case of N64itis. N64itis by Russ Rebellion July 19, 2011 0 0 Get merch Get the N64itis mug. Buy Now — $32.95 See more merch
