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1.
Commonly abbreviated MLM, it's a form of selling a product whereby one person recruits other salespeople, who recruits other salespeople, ad nausea and after each sale, everybody above the salesman gets a small piece of commission. To make money in one (98%+ of people don't), one should place much more emphasis on recruiting than sales. Amway is probably the most well-known MLM.

Many MLMs have "optional" national meetings, motivational books and tapes, and other various expenses. The cost of these comes out of pocket of the individual. As a general rule, if you can be one of the first people to join a successful MLM, you'll make a lot of money, especially if you can sell all of this crap to your downline. However, if you're not in this lucky 1-2%, you'll honestly be lucky to break even in your expenses.

There is some technical difference between a pyramid scheme, which is illegal, and an MLM, which is legal. However, nobody but the high-priced lawyers which keep MLMs in business and stealing the money of its starry-eyed employees seem to know what this difference is.
There are too many Multi-Level Marketing organizations to count. After one is shut down by bankruptcy or the government, two new ones sprout from the ground.
by iLikeSoup March 12, 2011
 
2.
The full version of the more commonly used abbreviation, MLM.
MLM stands for Multi-Level Marketing.
by Downstrike June 04, 2004